Glycolide → HCID 131718652, compound

HRID 1742773Notes

Reaction equation

[CH3:1][C@@H:2]1[O:9][C:7](=[O:8])[C@H:6]([CH3:10])[O:5][C:3]1=[O:4].[CH2:11]1[O:18][C:16](=[O:17])[CH2:15][O:14][C:12]1=[O:13]>>[CH3:1][C@@H:2]1[O:9][C:7](=[O:8])[C@H:6]([CH3:10])[O:5][C:3]1=[O:4].[CH2:11]1[O:18][C:16](=[O:17])[CH2:15][O:14][C:12]1=[O:13].[C:7]1(=[O:8])[O:9][CH2:2][CH2:3][CH2:11][CH2:10][CH2:6]1

Participants

Reactant 2

HCID 65432Glycolide

HCID 107983Lactide, L-

Product 1

HCID 131718652HCID 131718652, compound

Conditions

Temperature: 200 °C

Procedure

l-Lactide (l-Lac, 153.3 grams) and Glycolide (Gly, 17.0 grams) were melted and charged into the reactor. The contents were stirred at 200° C. for 2 hours at which point the mixture had again obtained maximum melt viscosity. The polymer was discharged from the reactor, ground, and dried in a vacuum oven at 100° C. and 0.2 mm Hg. The polymer had in inherent viscosity of 1.40 dL/g in chloroform, measured at 30° C. on a 0.5% solution. The polymer composition, as measured by 1H-NMR spectroscopy was 15.9/74.1/10.0 weight percent CAP/l-LAC/Gly.

Workup

additioncharged into the reactor
customdried in a vacuum oven at 100° C.
custommeasured at 30° C. on a 0.5% solution

Sources & evidence

ORD record: ord-2c857926cf0c42938fc6bd78021b3d47
Source dataset: uspto-grants-1994_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05342395

Reaction notes

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