Nitroethane → HCID 69661384, compound

HRID 1743806Notes

Reaction equation

HRID 1743806 reaction equation
[OH:1][CH:2]1[CH2:14][O:13][C:12]2[CH:11]=[CH:10][C:9]3[NH:8][CH:7]=[C:6]([CH:15]=O)[C:5]=3[C:4]=2[CH2:3]1.C([O-])(=O)C.[NH4+].[N+:22]([CH2:25][CH3:26])([O-:24])=[O:23]>>[N+:22]([C:25]([CH3:26])=[CH:15][C:6]1[C:5]2[C:4]3[CH2:3][CH:2]([OH:1])[CH2:14][O:13][C:12]=3[CH:11]=[CH:10][C:9]=2[NH:8][CH:7]=1)([O-:24])=[O:23]

Participants

4

Reactant 3

HCID 6587NitroethaneHCID 517165Ammonium AcetateHCID 22236613HCID 22236613, compound

Product 1

HCID 69661384HCID 69661384, compound

Conditions

Temperature
115 °C

Procedure

A mixture of the product from Step D (0.64 g, 2.95 mmol) and ammonium acetate (0.23 g, 2.98 mmol) in nitroethane (3 ml) was heated at 115° C. for 2.5 h. The mixture was cooled and the orange solid that formed was collected by filtration, washed with EtOAc and water and dried under vacuum (0.54 g, 67%): mp 240-242° C.

Workup

  1. temperatureThe mixture was cooled
  2. customthe orange solid that formed
  3. filtrationwas collected by filtration
  4. washwashed with EtOAc and water
  5. customdried under vacuum (0.54 g, 67%)

Sources & evidence

ORD record
ord-5c0195593b154d9f8af3042f772b8507
Source dataset
uspto-grants-2006_03
Patent number
US07012090B1

Reaction notes

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