Dimethylformamide → 2-[5-Formyl-1-(2-trimethylsilanyl-ethoxymethyl)-1H-imidazol-2-yl]-pyrrolidine-1-carboxylic acid tert-butyl ester
Reaction equation
[Br:6][c:7]1[cH:8][n:9][c:10]([CH:20]2[N:21]([C:25](=[O:26])[O:27][C:28]([CH3:29])([CH3:30])[CH3:31])[CH2:22][CH2:23][CH2:24]2)[n:11]1[CH2:12][O:13][CH2:14][CH2:15][Si:16]([CH3:17])([CH3:18])[CH3:19].[CH2:1]([Li:2])[CH2:3][CH2:4][CH3:5].[CH3:32][N:33]([CH:34]=[O:35])[CH3:36].[O:37]1[CH2:38][CH2:39][CH2:40][CH2:41]1>>[c:7]1([CH:34]=[O:35])[cH:8][n:9][c:10]([CH:20]2[N:21]([C:25](=[O:26])[O:27][C:28]([CH3:29])([CH3:30])[CH3:31])[CH2:22][CH2:23][CH2:24]2)[n:11]1[CH2:12][O:13][CH2:14][CH2:15][Si:16]([CH3:17])([CH3:18])[CH3:19]Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-07555a412d7141d5a50502c94461dc19
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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