Dimethylformamide → 1'-[(6-Chloro-1H-indol-3-yl)carbonyl]-2-methyl-2,3-dihydrospiro[isoindole-1,4'-piperidine]
Reaction equation
[CH3:22][N:23]1[C:24]2([c:25]3[cH:26][cH:27][cH:28][cH:29][c:30]3[CH2:31]1)[CH2:32][CH2:33][NH:34][CH2:35][CH2:36]2.[CH3:37][CH2:38][N:39]([CH2:40][CH3:41])[CH2:42][CH3:43].[CH3:47][N:48]([CH3:49])[CH:50]=[O:51].[Cl:14][C:15]([N:16]([CH3:17])[CH3:18])=[C:19]([CH3:20])[CH3:21].[Cl:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([C:11](=[O:12])[OH:13])[cH:7][nH:8][c:9]2[cH:10]1.[Cl:44][CH2:45][Cl:46]>>[Cl:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([C:11](=[O:13])[N:34]3[CH2:33][CH2:32][C:24]4([N:23]([CH3:22])[CH2:31][c:30]5[c:25]4[cH:26][cH:27][cH:28][cH:29]5)[CH2:36][CH2:35]3)[cH:7][nH:8][c:9]2[cH:10]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-1780654ac8834bbca198168331179df5
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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