Dichloromethane → 1-(benzo[d]oxazol-2-yl)-N-(4-(3-(4-(dimethylamino)piperidin-1-yl)-1-(4-methoxybenzyl)-1H-pyrazolo[3,4-b]pyridin-4-yloxy)-3-fluorophenyl)cyclopropanecarboxamide
Reaction equation
[CH3:25][CH2:26][N:27]=[C:28]=[N:29][CH2:30][CH2:31][CH2:32][N:33]([CH3:34])[CH3:35].[CH:16]([N:17]([CH2:18][CH3:19])[CH:20]([CH3:21])[CH3:22])([CH3:23])[CH3:24].[Cl:72][CH2:73][Cl:74].[NH2:36][c:37]1[cH:38][c:39]([F:71])[c:40]([O:41][c:42]2[c:43]3[c:44]([n:45][cH:46][cH:47]2)[n:48]([CH2:60][c:61]2[cH:62][cH:63][c:64]([O:67][CH3:68])[cH:65][cH:66]2)[n:49][c:50]3[N:51]2[CH2:52][CH2:53][CH:54]([N:57]([CH3:58])[CH3:59])[CH2:55][CH2:56]2)[cH:69][cH:70]1.[o:1]1[c:2]([C:10]2([C:13](=[O:14])[OH:15])[CH2:11][CH2:12]2)[n:3][c:4]2[c:5]1[cH:6][cH:7][cH:8][cH:9]2>>[o:1]1[c:2]([C:10]2([C:13](=[O:15])[NH:36][c:37]3[cH:38][c:39]([F:71])[c:40]([O:41][c:42]4[c:43]5[c:44]([n:45][cH:46][cH:47]4)[n:48]([CH2:60][c:61]4[cH:62][cH:63][c:64]([O:67][CH3:68])[cH:65][cH:66]4)[n:49][c:50]5[N:51]4[CH2:52][CH2:53][CH:54]([N:57]([CH3:58])[CH3:59])[CH2:55][CH2:56]4)[cH:69][cH:70]3)[CH2:11][CH2:12]2)[n:3][c:4]2[c:5]1[cH:6][cH:7][cH:8][cH:9]2Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-d146721cc00b46bdb801be1a1d1d8091
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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