Methylamine → 4-{2-[2-Amino-6-(4-methylpiperazin-1-yl)pyrimidin-4-yl]-3-methyl-1,2,3,4-tetrahydroisoquinolin-7-yl}-N,1-dimethyl-1H-pyrrole-2-carboxamide
Reaction equation
[CH2:37]1[O:38][CH2:39][CH2:40][CH2:41]1.[CH3:35][NH2:36].[NH2:1][c:2]1[n:3][c:4]([N:28]2[CH2:29][CH2:30][N:31]([CH3:34])[CH2:32][CH2:33]2)[cH:5][c:6]([N:8]2[CH2:9][c:10]3[cH:11][c:12](-[c:19]4[cH:20][c:21]([C:25](=[O:26])[OH:27])[n:22]([CH3:24])[cH:23]4)[cH:13][cH:14][c:15]3[CH2:16][CH:17]2[CH3:18])[n:7]1>>[NH2:1][c:2]1[n:3][c:4]([N:28]2[CH2:29][CH2:30][N:31]([CH3:34])[CH2:32][CH2:33]2)[cH:5][c:6]([N:8]2[CH2:9][c:10]3[cH:11][c:12](-[c:19]4[cH:20][c:21]([C:25](=[O:26])[NH:36][CH3:35])[n:22]([CH3:24])[cH:23]4)[cH:13][cH:14][c:15]3[CH2:16][CH:17]2[CH3:18])[n:7]1Participants
4
Sources & evidence
- ORD record
- ord-4c3e828079c149779c7b8ccb3f78e5bf
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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