Dimethylformamide → 2-[1-[[5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl]acetyl]-4-piperidinyl]-4-thiazolecarbonyl chloride
Reaction equation
[CH3:1][c:2]1[cH:3][c:4]([C:24]([F:25])([F:26])[F:27])[n:5][n:6]1[CH2:7][C:8](=[O:9])[N:10]1[CH2:11][CH2:12][CH:13]([c:16]2[s:17][cH:18][c:19]([C:21](=[O:22])[OH:23])[n:20]2)[CH2:14][CH2:15]1.[CH3:28][N:29]([CH3:30])[CH:31]=[O:32].[Cl:33][C:34]([C:35]([Cl:36])=[O:37])=[O:38].[Cl:39][CH2:40][Cl:41]>>[CH3:1][c:2]1[cH:3][c:4]([C:24]([F:25])([F:26])[F:27])[n:5][n:6]1[CH2:7][C:8](=[O:9])[N:10]1[CH2:11][CH2:12][CH:13]([c:16]2[s:17][cH:18][c:19]([C:21](=[O:22])[Cl:33])[n:20]2)[CH2:14][CH2:15]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-d7e0a65de76b4a4d9fcd4f4517652dea
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
Loading…