Dimethylformamide → HCID 59457850, compound

HRID 175254Notes

Reaction equation

HRID 175254 reaction equation
[Br:1][c:2]1[cH:3][c:4]([F:32])[c:5](-[c:8]2[n:9][n:10][c:11]3[n:12]2[cH:13][c:14](-[c:17]2[c:18](-[c:25]4[cH:26][cH:27][c:28]([F:31])[cH:29][cH:30]4)[n:19][c:20]4[o:21][cH:22][cH:23][n:24]24)[cH:15][cH:16]3)[cH:6][cH:7]1.[NH2:33][CH2:34][C:35]([CH2:36][OH:37])([CH3:38])[CH3:39].[O:40]=[CH:41][N:42]([CH3:43])[CH3:44].[Pd:45]([Cl:46])[Cl:47].[c:48]1([P:49]([c:50]2[cH:51][cH:52][cH:53][cH:54][cH:55]2)[c:56]2[cH:57][cH:58][cH:59][cH:60][cH:61]2)[cH:62][cH:63][cH:64][cH:65][cH:66]1.[c:67]1([P:68]([c:69]2[cH:70][cH:71][cH:72][cH:73][cH:74]2)[c:75]2[cH:76][cH:77][cH:78][cH:79][cH:80]2)[cH:81][cH:82][cH:83][cH:84][cH:85]1>>[c:2]1([C:41]([NH:33][CH2:34][C:35]([CH2:36][OH:37])([CH3:38])[CH3:39])=[O:40])[cH:3][c:4]([F:32])[c:5](-[c:8]2[n:9][n:10][c:11]3[n:12]2[cH:13][c:14](-[c:17]2[c:18](-[c:25]4[cH:26][cH:27][c:28]([F:31])[cH:29][cH:30]4)[n:19][c:20]4[o:21][cH:22][cH:23][n:24]24)[cH:15][cH:16]3)[cH:6][cH:7]1

Participants

6

Reactant 5

HCID 6228DimethylformamideHCID 11776Triphenylphosphine2×HCID 24290Palladium ChlorideHCID 1173261-Propanol, 3-amino-2,2-dimethyl-HCID 59457821HCID 59457821, compound

Product 1

HCID 59457850HCID 59457850, compound

Sources & evidence

ORD record
ord-923db45dd8ba4cc9b6856a440871b194
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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