反应详情

Matairesinol (5 g, 13.95 mmol) was dissolved in DMF (20 ml) and potassium carbonate (9.64 g, 69.8 mmol), iodomethane (5.23 ml, 84 mmol) were added. The mixture was stirred at RT for 18 h and then DMF was partly evaporated under reduced pressure and mixture was diluted with water (50 ml). The formed insoluble oil was separated, dissolved in DCM, dried with Na2SO4 and evaporated to dryness to give 4.87 g, (90% yield) of dimethylmatairesinol as a yellowish powder.

1. customDMF was partly evaporated under reduced pressure and mixture
2. additionwas diluted with water (50 ml)
3. customThe formed insoluble oil was separated
4. dissolutiondissolved in DCM
5. dry with materialdried with Na2SO4
6. customevaporated to dryness