反应详情

温度

65 °C

To a solution of 1-(2-chloro-6-(methoxymethoxy)phenyl)ethanone (38 g, 177.03 mmol, 1.00 equiv) in THF (380 mL) was added HCl (aq. 35 g, 2.00 equiv, 36%). The resulting mixture was allowed to react, with stirring, for 3 h at 65° C. The resulting mixture was extracted with ethyl acetate. The organic phase was separated, dried and concentrated under vacuum to give the crude title compound.

1. customto react
2. extractionThe resulting mixture was extracted with ethyl acetate
3. customThe organic phase was separated
4. customdried
5. concentrationconcentrated under vacuum