Benzyl Bromide → HCID 71677834, compound

HRID 1754809Notes

Reaction equation

HRID 1754809 reaction equation
[CH2:1]([Br:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[O:9]1[CH:13]2[O:14][CH2:15][CH2:16][N:12]2[CH2:11][CH2:10]1>C(OC(C)C)(C)C>[Br-:8].[CH2:1]([N+:12]12[CH2:16][CH2:15][O:14][CH:13]1[O:9][CH2:10][CH2:11]2)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

4

Reactant 2

HCID 7498Benzyl BromideHCID 798431-Aza-4,6-dioxabicyclo(3.3.0)octane

Product 1

HCID 71677834HCID 71677834, compoundYield 94.3%

Reagents, catalysts & solvents 1

HCID 7914Diisopropyl EtherSolvent

Procedure

A solution of 1.710 g (10 mmol) of benzyl bromide and 1.152 g (10 mmol) of tetrahydro-[1,3]oxazolo[2,3-b][1,3]oxazole in 20 ml of diisopropyl ether was stirred at the room temperature for 24 hours. The precipitate was filtered off, washed twice with diisopropyl ether and dried. 2.698 g (94.3%) of white amorphous product was obtained, which can be further purified by recrystallisation from rectified ethanol.

Workup

  1. filtrationThe precipitate was filtered off
  2. washwashed twice with diisopropyl ether
  3. customdried

Sources & evidence

ORD record
ord-3bbed26aee7f4d4caee3818d303d1b6d
Source dataset
uspto-grants-2015_10
Patent number
US09169267B2

Reaction notes

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