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HRID1755537

反应详情

EQUATION

反应方程式

HRID 1755537 的结构方程式

REACTANTS

反应物

3
结构：CCCN
HCID7852

Propylamine

C3H9N

结构：Cc1c(C)c2c(c(C)c1O)CCC(C)(C(=O)O)O2
HCID40634

Trolox

C14H18O4

结构：O=C(n1ccnc1)n1ccnc1
HCID68263

1,1'-Carbonylbis(1H-imidazole)

C7H6N4O

PRODUCTS

生成物

1
结构：CCCNC(=O)C1(C)CCc2c(C)c(O)c(C)c(C)c2O1
HCID67262969

未命名化合物

收率 63.3%

PROCEDURE

实验过程

Following the amide coupling procedure described in protocol A, 502.3 mg 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid (2.01 mmol), 358 mg CDI (2.21 mmol) and 130 mg propylamine (2.20 mmol) produced 371 mg of 6-hydroxy-2,5,7,8-tetramethyl-N-propylchroman-2-carboxamide as an off white syrup.