3-Phenylprop-2-Enal → HCID 53914665, compound

HRID 1755766Notes

Reaction equation

HRID 1755766 reaction equation
[C:1]([NH2:5])([CH3:4])([CH3:3])[CH3:2].[CH:6](=O)[CH:7]=[CH:8][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1.CC(=O)CC>O>[C:1]([N:5]=[CH:6][CH:7]=[CH:8][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)([CH3:4])([CH3:3])[CH3:2]

Participants

5

Reactant 3

HCID 3073-Phenylprop-2-EnalHCID 6385Tert-ButylamineHCID 6569Methyl Ethyl Ketone

Product 1

HCID 53914665HCID 53914665, compoundYield 96%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

20.3 grams of t-butylamine (0.28 mol) was metered over a period of 16 minutes to 33.0 grams of cinnamaldehyde (0.25 mol) during stirring and cooling. The mixture was left to stand overnight at room temperature. 150 ml of butanone was then added to the crude reaction mixture to enable the water formed during the reaction to be evaporated azeotropically. The mixture was evaporated on a rotary evaporator. The residue consisted of 45.6 grams of product having a purity of 98%. Yield 96%.

Workup

  1. temperaturecooling
  2. waitThe mixture was left
  3. customreaction mixture
  4. customformed during the reaction
  5. customto be evaporated azeotropically
  6. customThe mixture was evaporated on a rotary evaporator

Sources & evidence

ORD record
ord-8ba4c3fabb234f6bbae56f113b1c5750
Source dataset
uspto-grants-1995_08
Patent number
US05438143

Reaction notes

Loading…