Hydrochloric Acid → 4-bromo-N-[4-(4-dimethylamino-quinazolin-2-ylamino)-phenyl]-2-trifluoromethoxy-benzenesulfonamide
Reaction equation
[Br:35][c:36]1[cH:37][c:38]([O:46][C:47]([F:48])([F:49])[F:50])[c:39]([S:42](=[O:43])(=[O:44])[Cl:45])[cH:40][cH:41]1.[C:1]([O:2][C:3](=[O:4])[NH:7][c:8]1[cH:9][cH:10][c:11]([NH:14][c:15]2[n:16][c:17]3[cH:18][cH:19][cH:20][cH:21][c:22]3[c:23]([N:25]([CH3:26])[CH3:27])[n:24]2)[cH:12][cH:13]1)([CH3:5])([CH3:6])[CH3:28].[CH3:51][CH2:52][O:53][C:54]([CH3:55])=[O:56].[Cl:57][CH2:58][Cl:59].[ClH:29].[Na+:34].[O-:30][C:31]([OH:32])=[O:33]>>[NH:7]([c:8]1[cH:9][cH:10][c:11]([NH:14][c:15]2[n:16][c:17]3[cH:18][cH:19][cH:20][cH:21][c:22]3[c:23]([N:25]([CH3:26])[CH3:27])[n:24]2)[cH:12][cH:13]1)[S:42]([c:39]1[c:38]([O:46][C:47]([F:48])([F:49])[F:50])[cH:37][c:36]([Br:35])[cH:41][cH:40]1)(=[O:43])=[O:44]Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-82841b5b64994e8e96f33a2b9f0c509a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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