Hydrochloric Acid → HCID 15341804, compound

HRID 1756197Notes

Reaction equation

HRID 1756197 reaction equation
[OH:1][C:2]1[C:11]([CH2:12][CH:13]=[CH2:14])=[C:10]([OH:15])[CH:9]=[CH:8][C:3]=1[C:4]([O:6]C)=O.[Cl-].[NH4+:17].Cl>N1CCCC1>[OH:1][C:2]1[C:11]([CH2:12][CH:13]=[CH2:14])=[C:10]([OH:15])[CH:9]=[CH:8][C:3]=1[C:4]([N:17]1[CH2:4][CH2:3][CH2:2][CH2:11]1)=[O:6]

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 25517Ammonium ChlorideHCID 13019279Methyl 2,4-dihydroxy-3-(prop-2-en-1-yl)benzoate

Product 1

HCID 15341804HCID 15341804, compound

Reagents, catalysts & solvents 1

HCID 31268PyrrolidineSolvent

Conditions

Temperature
50 °C

Procedure

Methyl 2,4-dihydroxy-3-(2-propenyl)benzoate (3.0 g) and a few crystals of ammonium chloride were added to 20 ml of pyrrolidine. The reaction mixture was heated to 50° C. and stirred overnight. The reaction mixture was neutralized with 10% hydrochloric acid and extracted with ethyl acetate. Concentration under vacuum to remove solvent gave the product as a light brown solid.

Workup

  1. extractionextracted with ethyl acetate
  2. concentrationConcentration under vacuum
  3. customto remove solvent

Sources & evidence

ORD record
ord-73e30d27329245d5827d26be49bd9a9d
Source dataset
uspto-grants-1995_08
Patent number
US05439937

Reaction notes

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