反应详情

To a solution of 4-formyl-3-thienylboronic acid (1.0 g, 6.4 mmol) in dry THF (10 ml) sodium borohydride (0.27 g, 7.1 mmol) was added. The mixture was stirred at room temperature for 30 minutes. The reaction was then stopped by the addition of 1M hydrochloric acid and was then extracted with ethyl acetate, dried and evaporated to dryness. Yield: 0.9 g, 89%, dec. at ≈120° C.

1. extractionwas then extracted with ethyl acetate
2. customdried
3. customevaporated to dryness
4. customat ≈120° C.