Trichloroacetyl chloride → HCID 19387630, compound

HRID 1757342Notes

Reaction equation

HRID 1757342 reaction equation
[CH2:1]=[C:2]1[CH2:7][CH2:6][CH:5]([C:8]2[CH:13]=[C:12]([F:14])[C:11]([F:15])=[C:10]([F:16])[CH:9]=2)[CH2:4][CH2:3]1.FC1C=C([Mg]Br)C=C(F)C=1F.C1(=O)CCC(=O)CC1.[Cl:36][C:37](Cl)([Cl:41])[C:38](Cl)=O>O>[F:16][C:10]1[CH:9]=[C:8]([CH:5]2[CH2:6][CH2:7][C:2]3([C:37]([Cl:41])([Cl:36])[CH2:38][CH2:1]3)[CH2:3][CH2:4]2)[CH:13]=[C:12]([F:14])[C:11]=1[F:15]

Participants

6

Reactant 4

HCID 6420Trichloroacetyl chlorideHCID 125111,4-CyclohexanedioneHCID 19387600HCID 19387600, compoundHCID 178505944HCID 178505944, compound

Product 1

HCID 19387630HCID 19387630, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

0.1 mol of 4-methylene-1-(3,4,5-trifluorophenyl)-cyclohexane (obtainable by reacting 3,4,5-trifluorophenylmagnesium bromide with the monoethylene ketal of cyclohexane-1,4-dione followed by elimination of water, hydrogenation and ketal cleavage) and 0.1 mol of trichloroacetyl chloride are reacted in accordance with Example 1B.

Workup

  1. customare reacted in accordance with Example 1B

Sources & evidence

ORD record
ord-0af4a9a3c6fe46809c491cfd157ec4df
Source dataset
uspto-grants-1995_08
Patent number
US05445764

Reaction notes

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