Dimethylformamide → HCID 57075905, compound

HRID 1757614Notes

Reaction equation

HRID 1757614 reaction equation
[C:1]([O:6][CH2:7][CH3:8])(=[O:5])[CH2:2][CH2:3][CH3:4].[CH3:9][N:10]([CH:12]=O)[CH3:11]>>[CH3:9][N:10]([CH3:12])[CH:11]=[C:2]([CH2:3][CH3:4])[C:1]([O:6][CH2:7][CH3:8])=[O:5]

Participants

3

Reactant 2

HCID 6228DimethylformamideHCID 7762Ethyl butyrate

Product 1

HCID 57075905HCID 57075905, compound

Procedure

In a distillation apparatus, 86 g of t-butylaminal ester and 87 g of ethyl butyrate in 100 ml of DMF were heated so that the alcohol distilled off slowly. Distillation of the product gave 73.8 g of ethyl β-dimethylamino-2ethylacrylate, corresponding to 87.3% of the theoretical yield.

Workup

  1. distillationdistilled off slowly
  2. distillationDistillation of the product

Sources & evidence

ORD record
ord-b650e03136a84f07b11ccb9db2ffbf7d
Source dataset
uspto-grants-1995_08
Patent number
US05446192

Reaction notes

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