Water → Benzonitrile, 3,4-dihydroxy-5-nitro-

HRID 1757670Notes

Reaction equation

HRID 1757670 reaction equation
[OH:1][C:2]1[CH:3]=[C:4]([CH:7]=[C:8]([N+:11]([O-:13])=[O:12])[C:9]=1[OH:10])[CH:5]=O.Cl.[NH2:15]O.O>C(O)=O>[OH:1][C:2]1[CH:3]=[C:4]([CH:7]=[C:8]([N+:11]([O-:13])=[O:12])[C:9]=1[OH:10])[C:5]#[N:15]

Participants

5

Reactant 3

HCID 962WaterHCID 443297Hydroxyamine hydrochlorideHCID 57489573,4-Dihydroxy-5-nitrobenzaldehyde

Product 1

HCID 5748958Benzonitrile, 3,4-dihydroxy-5-nitro-

Reagents, catalysts & solvents 1

HCID 284Formic AcidSolvent

Procedure

A solution containing 0.92 g of 3,4-dihydroxy-5-nitrobenzaidehyde. and 0.49g of hydroxylamine hydrochloride in 5.0 ml of formic acid was refluxed for 1 h. 50 ml of water was added and the product was filtered and washed withwater. Yield 0.3 g (33%), m.p. 175°-178° C.

Workup

  1. filtrationthe product was filtered
  2. washwashed withwater

Sources & evidence

ORD record
ord-e20e1f87cb2b4394b355c3d6f4fb2b5a
Source dataset
uspto-grants-1995_08
Patent number
US05446194

Reaction notes

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