Chlorotriethylsilane → HCID 20510336, compound

HRID 1757931Notes

Reaction equation

HRID 1757931 reaction equation
[Na].[N:2]1[C:6]2[CH:7]=[CH:8][CH:9]=[CH:10][C:5]=2[NH:4][C:3]=1[NH:11][C:12]([O:14][CH3:15])=[O:13].[CH2:16]([Si:18]([CH2:22][CH3:23])([CH2:20][CH3:21])Cl)[CH3:17]>CN(C)C=O>[CH2:16]([Si:18]([CH2:22][CH3:23])([CH2:20][CH3:21])[N:11]([C:3]1[NH:2][C:6]2[CH:7]=[CH:8][CH:9]=[CH:10][C:5]=2[N:4]=1)[C:12]([O:14][CH3:15])=[O:13])[CH3:17]

Participants

5

Reactant 3

HCID 13819ChlorotriethylsilaneHCID 25429CarbendazimHCID 5360545Sodium

Product 1

HCID 20510336HCID 20510336, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

5 parts of the resulting sodium salt of methyl benzimidazolecarbamate are suspended in 15 parts of dimethylformamide and 3.9 parts of triethylchlorosilane are added, in portions, at room temperature. After stirring the mixture for 12 hours under nitrogen, the solvent is distilled off under reduced pressure, tetrahydrofuran is added to the residue, and the solution is filtered. The solvent is then distilled off, giving 2.7 parts of methyl N-triethylsilyl-benzimidazole-2-carbamate; decomposition point >120° C. (active ingredient No. 1).

Workup

  1. additionare added, in portions, at room temperature
  2. distillationthe solvent is distilled off under reduced pressure, tetrahydrofuran
  3. additionis added to the residue
  4. filtrationthe solution is filtered
  5. distillationThe solvent is then distilled off

Sources & evidence

ORD record
ord-d60c42fd971a493ca6643d15be0f2c34
Source dataset
uspto-grants-1983_02
Patent number
US04371525

Reaction notes

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