Triglycidylglycerol → 1,2,3-Tris[2-hydroxy-3-(7,7,9,9-tetramethyl-3-octyl-2,4-dioxo-1,3,8-triazaspiro[4.5]dec-8-yl)propoxy]propane

HRID 1758205Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1758205
[CH3:1][C:2]1([CH3:24])[NH:21][C:20]([CH3:23])([CH3:22])[CH2:19][C:4]2([NH:8][C:7](=[O:9])[N:6]([CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH3:17])[C:5]2=[O:18])[CH2:3]1.[O:25]1[CH2:42][CH:26]1[CH2:27][O:28][CH2:29][CH:30]([CH2:36][O:37][CH2:38][CH:39]1[O:41][CH2:40]1)[O:31][CH2:32][CH:33]1[O:35][CH2:34]1>C(O)CCCCCCC>[OH:25][CH:26]([CH2:42][N:21]1[C:20]([CH3:23])([CH3:22])[CH2:19][C:4]2([NH:8][C:7](=[O:9])[N:6]([CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH3:17])[C:5]2=[O:18])[CH2:3][C:2]1([CH3:1])[CH3:24])[CH2:27][O:28][CH2:29][CH:30]([O:31][CH2:32][CH:33]([OH:35])[CH2:34][N:21]1[C:20]([CH3:23])([CH3:22])[CH2:19][C:4]2([NH:8][C:7](=[O:9])[N:6]([CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH3:17])[C:5]2=[O:18])[CH2:3][C:2]1([CH3:1])[CH3:24])[CH2:36][O:37][CH2:38][CH:39]([OH:41])[CH2:40][N:21]1[C:20]([CH3:23])([CH3:22])[CH2:19][C:4]2([NH:8][C:7](=[O:9])[N:6]([CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH3:17])[C:5]2=[O:18])[CH2:3][C:2]1([CH3:1])[CH3:24]

Komponenten

4

Edukt 2

HCID 25795TriglycidylglycerolHCID 112677117,7,9,9-Tetramethyl-3-octyl-1,3,8-triazaspiro[4.5]decane-2,4-dione

Produkt 1

HCID 205105851,2,3-Tris[2-hydroxy-3-(7,7,9,9-tetramethyl-3-octyl-2,4-dioxo-1,3,8-triazaspiro[4.5]dec-8-yl)propoxy]propane

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 9571-OctanolLösungsmittel

Reaktionsbedingungen

Temperatur
180 °C

Versuchsvorschrift

A mixture of 11.0 g of 7,7,9,9-tetramethyl-3-octyl-1,3,8-triazaspiro[4.5]decane-2,4-dione and 2.6 g of glycerol tris(2,3-epoxypropyl)ether in 10 ml of octanol was heated at 180° C. for 30 hours. After completion of the reaction, the reaction mixture was purified by column chromatography through silica gel eluted with ethyl acetate, giving the desired Compound No. 349 in the form of a colourless oil. The compound had an Rf value of 0.54 on thin-layer chromatography on silica gel when developed with a 10:1 by volume mixture of ethyl acetate and triethylamine.

Aufarbeitung

  1. customAfter completion of the reaction
  2. customthe reaction mixture was purified by column chromatography through silica gel
  3. washeluted with ethyl acetate

Quellen und Nachweise

ORD-Eintrag
ord-a71dc88bbf9245bdb2dd4e207ba3866f
Quelldatensatz
uspto-grants-1983_02
Patentnummer
US04371644

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