Trimethyl phosphite → Hosphinecarboxylic acid, dimethoxy-, 3,4-dichlorophenyl ester, oxide

HRID 1758225Notes

Reaction equation

C[O:2][P:3]([O:6][CH3:7])[O:4][CH3:5].Cl[C:9]([O:11][C:12]1[CH:17]=[CH:16][C:15]([Cl:18])=[C:14]([Cl:19])[CH:13]=1)=[O:10]>>[Cl:19][C:14]1[CH:13]=[C:12]([CH:17]=[CH:16][C:15]=1[Cl:18])[O:11][C:9]([P:3](=[O:2])([O:6][CH3:7])[O:4][CH3:5])=[O:10]

Participants

Reactant 2

HCID 8472Trimethyl phosphite

HCID 130778903,4-Dichlorophenyl carbonochloridate

Product 1

HCID 512117Hosphinecarboxylic acid, dimethoxy-, 3,4-dichlorophenyl ester, oxide

Procedure

From 10.3 g (85 mmole) of trimethylphosphite and 13.5 g (60 mmole) of 3,4-dichlorophenyl chloroformate (100°, 2 hours). Yield 11.4 g (64%) B.p.0.04 164° C. nD20 1.5271. Solidifies to colourless crystals m.p. 58°-9° C.

Sources & evidence

ORD record: ord-9bbc1da9d361477baae0a0e4d846f837
Source dataset: uspto-grants-1983_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04372894

Reaction notes

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