Pyridine → HCID 62998541, compound

HRID 1758238Notes

Reaction equation

HRID 1758238 reaction equation
[NH2:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8](=[O:10])[CH3:9].[C:11]1(C)[CH:16]=[CH:15][C:14]([S:17](Cl)(=[O:19])=[O:18])=[CH:13][CH:12]=1.N1C=CC=C[CH:23]=1>>[C:13]1([CH3:23])[CH:12]=[CH:11][CH:16]=[CH:15][C:14]=1[S:17]([NH:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8](=[O:10])[CH3:9])(=[O:18])=[O:19]

Participants

4

Reactant 3

HCID 1049PyridineHCID 73974-Toluenesulfonyl chlorideHCID 110862'-Aminoacetophenone

Product 1

HCID 62998541HCID 62998541, compound

Procedure

25 g of o-aminoacetophenone and 40 g of p-toluene sulfonyl chloride are together dissolved in 150 ml of pyridine and are left to stand at 50°-60° for one hour. The reaction mixture is then added to 1 liter of a stirred ice-water mixture and extracted with methylene chloride after half an hour.

Workup

  1. waitare left
  2. extractionextracted with methylene chloride after half an hour

Sources & evidence

ORD record
ord-f7136b19a0e7465486e325a9596f706b
Source dataset
uspto-grants-1983_02
Patent number
US04372956

Reaction notes

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