Methylparaben → HCID 178428978, compound

HRID 1758455Notes

Reaction equation

HRID 1758455 reaction equation
C[O:2][C:3]([C:5]1[CH:6]=[CH:7][C:8]([OH:11])=[CH:9][CH:10]=1)=[O:4].[OH-].[Na+].O.O.[C:16]([O-])(=O)C.[Zn+2:20].[C:21]([O-:24])(=[O:23])[CH3:22].[Na]>O>[CH3:16][C:10]1[CH:9]=[C:8]([OH:11])[CH:7]=[CH:6][C:5]=1[C:3]([O-:2])=[O:4].[CH3:5][C:6]1[CH:7]=[C:8]([OH:11])[CH:9]=[CH:10][C:22]=1[C:21]([O-:24])=[O:23].[Zn+2:20]

Participants

6

Reactant 4

HCID 7456MethylparabenHCID 14798Sodium HydroxideHCID 2724192Zinc acetate (USP)HCID 5360545Sodium

Product 1

HCID 178428978HCID 178428978, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent2×

Procedure

To a suspension of 17.5 parts (0.115 mole) of methyl p-hydroxybenzoate in 40 grams of water that had been cooled to 0°-10° C. was slowly added a 50% aqueous sodium hydroxide solution until the pH of the resulting solution was 12. A solution of 12.6 parts (0.06 mole) of zinc acetate dihydrate in 200 parts of water was added to the sodium salt solution. The white precipitate that formed was separated by filtration, washed with cold water, and dried. There was obtained 19.2 parts of zinc bis(methyl p-hydroxybenzoate).

Workup

  1. temperaturehad been cooled to 0°-10° C.
  2. customThe white precipitate that formed
  3. customwas separated by filtration
  4. washwashed with cold water
  5. customdried

Sources & evidence

ORD record
ord-7e9afb6a372942169bcb916681c72e93
Source dataset
uspto-grants-1983_02
Patent number
US04373953

Reaction notes

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