HCID 13105135, compound → HCID 131712960, compound

HRID 1758467Notes

Reaction equation

HRID 1758467 reaction equation
[NH:1](C(OC(C)(C)C)=O)[C@H:2]([C:10]([N:12]([CH3:31])[C@H:13]([C:15]([NH:17][C@H:18]([C:27]([O:29][CH3:30])=[O:28])[CH2:19][C:20]1[CH:25]=[CH:24][C:23]([OH:26])=[CH:22][CH:21]=1)=[O:16])[CH3:14])=[O:11])[CH2:3][C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1>C(OC(=O)C)C.Cl>[NH2:1][C@H:2]([C:10]([N:12]([CH3:31])[C@H:13]([C:15]([NH:17][C@H:18]([C:27]([O:29][CH3:30])=[O:28])[CH2:19][C:20]1[CH:25]=[CH:24][C:23]([OH:26])=[CH:22][CH:21]=1)=[O:16])[CH3:14])=[O:11])[CH2:3][C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1

Participants

4

Reactant 1

HCID 13105135HCID 13105135, compound

Product 1

HCID 131712960HCID 131712960, compound

Reagents, catalysts & solvents 2

HCID 313Hydrochloric AcidSolventHCID 8857Ethyl AcetateSolvent

Procedure

Following the procedure of Example 2 using 73.37 grams of BOC-Phe-N-Me-Ala-Tyr-OMe in 500 ml of ethylacetate and hydrogen chloride gas there is obtained 3 crops of "Phe-N-Me-Ala-Tyr-OMe" as follows:

Sources & evidence

ORD record
ord-b3e6110308574a8fb8f7ca29e6111f84
Source dataset
uspto-grants-1983_02
Patent number
US04374060

Reaction notes

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