Ethanol → HCID 22598782, compound

HRID 1759666Notes

Reaction equation

HRID 1759666 reaction equation
Cl[C:2]1[N:7]=[C:6](OC)[C:5]([N+:10]([O-:12])=[O:11])=[CH:4][CH:3]=1.[NH:13]1[CH2:18][CH2:17][CH2:16][CH2:15][CH2:14]1.[CH2:19]([OH:21])C>>[CH3:19][O:21][C:2]1[CH:3]=[CH:4][C:5]([N+:10]([O-:12])=[O:11])=[C:6]([N:13]2[CH2:18][CH2:17][CH2:16][CH2:15][CH2:14]2)[N:7]=1

Participants

4

Reactant 3

HCID 702EthanolHCID 8082PiperidineHCID 107977036-Chloro-2-methoxy-3-nitropyridine

Product 1

HCID 22598782HCID 22598782, compound

Procedure

4 g (0.02 mol) of 6-chloro-2-methoxy-3-nitropyridine, 60 ml of ethanol and 4.2 ml of piperidine are charged to a fully equipped round-bottomed flask. The mixture is brought to reflux for two hours with stirring and then the mixture is poured onto an ice/water mixture with stirring. The precipitate formed is filtered off and dried. 2 g of yellow powder are obtained, Yd=42.5%.

Workup

  1. temperatureto reflux for two hours
  2. stirringwith stirring
  3. customThe precipitate formed
  4. filtrationis filtered off
  5. customdried

Sources & evidence

ORD record
ord-b6333113a9f34f24994a594f8b23819f
Source dataset
uspto-grants-2005_01
Patent number
US06837908B2

Reaction notes

Loading…