Methanol → Hydrochloric Acid

HRID 176132Notes

Reaction equation

HRID 176132 reaction equation
[CH2:18]1[CH2:19][CH2:20][NH:21][CH2:22][CH2:23]1.[CH3:26][OH:27].[Cl:1][CH:2]([C:3](=[O:4])[c:5]1[c:6]([CH:14]([CH3:15])[CH3:16])[n:7][n:8]2[c:9]1[cH:10][cH:11][cH:12][cH:13]2)[CH3:17].[I-:24].[Na+:25]>>[CH:2]([C:3](=[O:4])[c:5]1[c:6]([CH:14]([CH3:15])[CH3:16])[n:7][n:8]2[c:9]1[cH:10][cH:11][cH:12][cH:13]2)([CH3:17])[N:21]1[CH2:20][CH2:19][CH2:18][CH2:23][CH2:22]1.[ClH:1]

Participants

7

Reactant 5

HCID 887MethanolHCID 923Sodium ionHCID 8082PiperidineHCID 30165Iodide IonHCID 215857512-Chloro-1-[2-(1-methylethyl)pyrazolo[1,5-a]pyridin-3-yl]-1-propanone

Product 2

HCID 313Hydrochloric AcidHCID 578375082-Piperidin-1-yl-1-(2-propan-2-ylpyrazolo[1,5-a]pyridin-3-yl)propan-1-one

Sources & evidence

ORD record
ord-bc695ea725f54db5a39b2f5dcfbdd315
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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