Dichloromethane → tert-Butyl 4-(dimethylcarbamoyl)piperazine-1-carboxylate

HRID 176168Notes

Reaction equation

HRID 176168 reaction equation
[C:1](=[O:2])([O:3][C:4]([CH3:5])([CH3:6])[CH3:7])[N:8]1[CH2:9][CH2:10][NH:11][CH2:12][CH2:13]1.[CH3:14][N:15]([C:16](=[O:17])[Cl:18])[CH3:19].[Cl:25][CH2:26][Cl:27].[O:20]1[CH2:21][CH2:22][CH2:23][CH2:24]1>>[C:1](=[O:2])([O:3][C:4]([CH3:5])([CH3:6])[CH3:7])[N:8]1[CH2:9][CH2:10][N:11]([C:16]([N:15]([CH3:14])[CH3:19])=[O:17])[CH2:12][CH2:13]1

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 6598Dimethylcarbamoyl ChlorideHCID 8028TetrahydrofuranHCID 143452tert-Butyl piperazine-1-carboxylate

Product 1

HCID 22665738tert-Butyl 4-(dimethylcarbamoyl)piperazine-1-carboxylate

Sources & evidence

ORD record
ord-02fed4d45c2740a39825af48e8e15b6c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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