反应详情

40 g (0.2 mol) of ethyl α-ethoxalylpropionate are added to a suspension of 5.5 g (0.2 mol) of 80% strength sodium hydride in 300 ml of absolute xylene at 70° C. When the evolution of hydrogen has ended, 31.2 g (0.2 mol) of β-naphthaldehyde, dissolved in xylene, are added dropwise, and when the addition has ended the mixture is heated at the boiling point for 90 minutes. 150 ml of water are added to the cooled reaction mixture and the organic phase is separated off, washed with 7% strength sodium carbonate solution, dried over sodium sulphate and concentrated. The residue is distilled in vacuo. 21.7 g (45.2% of theory) of ethyl 2-methyl-3-β-naphthyl-acrylate of boiling point 110° C./0.13 mbar are obtained.

1. additionare added dropwise
2. additionwhen the addition
3. temperatureis heated at the boiling point for 90 minutes
4. customthe organic phase is separated off
5. washwashed with 7% strength sodium carbonate solution
6. dry with materialdried over sodium sulphate
7. concentrationconcentrated
8. distillationThe residue is distilled in vacuo