P-Toluic Acid → HCID 14426626, compound

HRID 1762175Notes

Reaction equation

HRID 1762175 reaction equation
[NH2:1][CH2:2][CH2:3][O:4][C:5]1[CH:14]=[CH:13][C:8]([C:9]([O:11][CH3:12])=[O:10])=[CH:7][CH:6]=1.[CH3:15][C:16]1[CH:24]=[CH:23][C:19]([C:20](O)=[O:21])=[CH:18][CH:17]=1.C1(N=C=NC2CCCCC2)CCCCC1>CN(C)C=O>[CH3:15][C:16]1[CH:24]=[CH:23][C:19]([C:20]([NH:1][CH2:2][CH2:3][O:4][C:5]2[CH:14]=[CH:13][C:8]([C:9]([O:11][CH3:12])=[O:10])=[CH:7][CH:6]=2)=[O:21])=[CH:18][CH:17]=1

Participants

5

Reactant 3

HCID 7470P-Toluic AcidHCID 10868DicyclohexylcarbodiimideHCID 14097616Methyl 4-(2-aminoethoxy)benzoate

Product 1

HCID 14426626HCID 14426626, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

Methyl 4-(2-aminoethoxy)benzoate (5.86 g) and 4.08 g of p-methylbenzoic acid were dissolved in 100 ml of N,N-dimethylformamide and then 6.19 g of N,N'-dicyclohexylcarbodiimide was gradually added thereto with stirring at room temperature.

Sources & evidence

ORD record
ord-d6ba0231e09247259ce2290d874d24ce
Source dataset
uspto-grants-1989_05
Patent number
US04831055

Reaction notes

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