Benzaldehyde → 1-Amino-2-ethylimidazole hydrochloride

HRID 1762357Notes

Reaction equation

HRID 1762357 reaction equation
C(=[N:8][N:9]1[CH:13]=[CH:12][N:11]=[C:10]1[CH2:14][CH3:15])C1C=CC=CC=1.C(=O)C1C=CC=CC=1.[ClH:24]>>[ClH:24].[NH2:8][N:9]1[CH:13]=[CH:12][N:11]=[C:10]1[CH2:14][CH3:15]

Participants

4

Reactant 3

HCID 240BenzaldehydeHCID 313Hydrochloric AcidHCID 540911721-Benzylideneamino-2-ethylimidazole

Product 1

HCID 200429171-Amino-2-ethylimidazole hydrochloride

Procedure

A solution of 19.9 g (0.1 mol) of 1-benzylideneamino-2-ethyl-imidazole in 200 ml of 1.5N hydrochloric acid is subjected to a steam distillation until benzaldehyde no longer results. The mixture is evaporated and the product obtained is recrystallized from ethanol/ether. There are obtained 14.5 g of 1-amino-2-ethylimidazole hydrochloride of melting point 90°-91°.

Workup

  1. customno longer results
  2. customThe mixture is evaporated
  3. customthe product obtained
  4. customis recrystallized from ethanol/ether

Sources & evidence

ORD record
ord-3a204012315c46d481efba4764e54797
Source dataset
uspto-grants-1989_05
Patent number
US04831151

Reaction notes

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