Sodium Carbonate → HCID 70393879, compound

HRID 1762398Notes

Reaction equation

HRID 1762398 reaction equation
[CH:1]1([CH:7]([CH:9]2[CH2:14][CH2:13][CH2:12][CH2:11][CH2:10]2)[NH2:8])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[C:15](=O)([O-])[O-].[Na+].[Na+].Br[CH2:22][C:23]([O:25]C)=[O:24]>CO>[CH3:15][N:8]([CH:7]([CH:1]1[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1)[CH:9]1[CH2:10][CH2:11][CH2:12][CH2:13][CH2:14]1)[CH2:22][C:23]([OH:25])=[O:24]

Participants

5

Reactant 3

HCID 10340Sodium CarbonateHCID 60984Methyl bromoacetateHCID 10774245alpha-Cyclohexylcyclohexanemethanamine

Product 1

HCID 70393879HCID 70393879, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

111 Parts of α-cyclohexylcyclohexanemethanamine and 60 parts of sodium carbonate were dispersed in 320 parts of methanol. 54 Parts of methyl bromoacetate were added dropwise to this dispersion. The mixture was stirred at room temperature for 72 hours. The precicitate was separated and the solution was concentrated to dryness, yielding methyl N-[(dicyclohexyl)methyl]glycine quantitatively (int. 1).

Workup

  1. customThe precicitate was separated
  2. concentrationthe solution was concentrated to dryness

Sources & evidence

ORD record
ord-98ba4f0a8a5a466c91f16bb464aa114c
Source dataset
uspto-grants-1989_05
Patent number
US04832732

Reaction notes

Loading…