反应详情

Reaction of 4-(1-acetylpiperidin-4-yl)benzenesulphonyl chloride (16.0 g) [the product of Example 2(i)] with an excess of aqueous methylamine (100 ml, 30%) in ethanol (10 ml) according to the method of Example 2(ii) gave the title compound, (15.0 g), used directly in the next stage.