Tetrahydrofuran → [3-(2,4-Dimethylphenyl)phenyl]methanol

HRID 176323Notes

Reaction equation

HRID 176323 reaction equation
[Al+3:21].[CH3:1][c:2]1[c:3](-[c:9]2[cH:10][c:11]([C:15](=[O:16])[O:17][CH2:18][CH3:19])[cH:12][cH:13][cH:14]2)[cH:4][cH:5][c:6]([CH3:8])[cH:7]1.[H-:20].[H-:23].[H-:24].[H-:25].[Li+:22].[O:26]1[CH2:27][CH2:28][CH2:29][CH2:30]1>>[CH3:1][c:2]1[c:3](-[c:9]2[cH:10][c:11]([CH2:15][OH:16])[cH:12][cH:13][cH:14]2)[cH:4][cH:5][c:6]([CH3:8])[cH:7]1

Participants

6

Reactant 5

HCID 8028TetrahydrofuranHCID 28486Lithium ionHCID 104727Aluminum CationHCID 166653Hydride4×HCID 23111852Ethyl 2',4'-dimethyl[1,1'-biphenyl]-3-carboxylate

Product 1

HCID 23111675[3-(2,4-Dimethylphenyl)phenyl]methanol

Sources & evidence

ORD record
ord-60cd8ebd7892499d8fb20c051e87a521
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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