Hydrochloric Acid → HCID 20309469, compound

HRID 1763314Notes

Reaction equation

HRID 1763314 reaction equation
[Cl-].[Al+3].[Cl-].[Cl-].[C:5]([C:7]1[CH:12]=[CH:11][C:10]([OH:13])=[CH:9][CH:8]=1)#[N:6].[C:14]1(=[O:20])[O:19][C:17](=[O:18])[CH2:16][CH2:15]1.Cl>C(Cl)(Cl)C(Cl)Cl>[C:5]([C:7]1[CH:8]=[CH:9][C:10]([OH:13])=[C:11]([CH:12]=1)[C:14]([CH2:15][CH2:16][C:17]([OH:19])=[O:18])=[O:20])#[N:6]

Participants

6

Reactant 4

HCID 313Hydrochloric AcidHCID 7922Succinic anhydrideHCID 130194-CyanophenolHCID 6451240Aluminum(III) Chloride

Product 1

HCID 20309469HCID 20309469, compound

Reagents, catalysts & solvents 1

HCID 65911,1,2,2-TetrachloroethaneSolvent

Procedure

Aluminium chloride (148 g, 1.11 mole) was added to a stirred mixture of 4-cyanophenol (44 g, 0.37 mole), succinic anhydride (33.3 g, 0.33 mole), and sym-tetrachloroethane (260 ml), and the mixture was then heated at 135° for 2 hours. The resultant complex was decomposed with ice and hydrochloric acid, and 3-(5-cyano-2-hydroxybenzoyl)propionic acid was isolated by standard procedures.

Workup

  1. temperaturethe mixture was then heated at 135° for 2 hours

Sources & evidence

ORD record
ord-296307cc7e304a82b661173469065830
Source dataset
uspto-grants-1978_09
Patent number
US04111936

Reaction notes

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