Triethylamine → HCID 22769263, compound

HRID 1764693Notes

Reaction equation

HRID 1764693 reaction equation
[CH3:1][C:2]1[NH:3][N:4]([CH2:14][C:15]2[CH:20]=[CH:19][C:18]([Cl:21])=[CH:17][CH:16]=2)[C:5](=[O:13])[C:6]=1[C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1.C(N(CC)CC)C.[Cl:29][C:30]1[CH:38]=[CH:37][C:33]([C:34](Cl)=[O:35])=[CH:32][CH:31]=1>O1CCOCC1>[Cl:29][C:30]1[CH:38]=[CH:37][C:33]([C:34]([O:13][C:5]2[N:4]([CH2:14][C:15]3[CH:16]=[CH:17][C:18]([Cl:21])=[CH:19][CH:20]=3)[N:3]=[C:2]([CH3:1])[C:6]=2[C:7]2[CH:8]=[CH:9][CH:10]=[CH:11][CH:12]=2)=[O:35])=[CH:32][CH:31]=1

Participants

5

Reactant 3

HCID 8471TriethylamineHCID 85014-Chlorobenzoyl chlorideHCID 22769179HCID 22769179, compound

Product 1

HCID 22769263HCID 22769263, compound

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent2×

Procedure

0.1 mol (29.9 g) of 3-methyl-4-phenyl-1-(p-chlorobenzyl)-5-pyrazolone were dissolved in 400 ml of absolute dioxane. After adding 15 ml of triethylamine, 0.11 mol (17.6 g) of 4-chlorobenzoyl chloride in dioxane was added dropwise. After heating for several hours under reflux, the reaction batch was worked up as follows:

Workup

  1. additionwas added dropwise
  2. temperatureAfter heating for several hours
  3. temperatureunder reflux

Sources & evidence

ORD record
ord-59a8a978602844e2905d7b84c2d24962
Source dataset
uspto-grants-1978_09
Patent number
US04117143

Reaction notes

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