Dimethyl Sulfoxide → 1-[[4-Thiophen-2-ylsulfonyl-1-[4-(1,1,1-trifluoro-2-hydroxypropan-2-yl)phenyl]piperazin-2-yl]methyl]piperidin-4-one
Reaction equation
[CH3:46][CH2:47][N:48]([CH2:49][CH3:50])[CH2:51][CH3:52].[CH3:7][S:8]([CH3:9])=[O:10].[Cl:1][C:2]([C:3]([Cl:4])=[O:5])=[O:6].[Cl:58][CH2:59][Cl:60].[Na+:57].[O-:53][C:54]([OH:55])=[O:56].[s:11]1[c:12]([S:16](=[O:17])(=[O:18])[N:19]2[CH2:20][CH:21]([CH2:38][N:39]3[CH2:40][CH2:41][CH:42]([OH:45])[CH2:43][CH2:44]3)[N:22]([c:25]3[cH:26][cH:27][c:28]([C:31]([C:32]([F:33])([F:34])[F:35])([CH3:36])[OH:37])[cH:29][cH:30]3)[CH2:23][CH2:24]2)[cH:13][cH:14][cH:15]1>>[s:11]1[c:12]([S:16](=[O:17])(=[O:18])[N:19]2[CH2:20][CH:21]([CH2:38][N:39]3[CH2:40][CH2:41][C:42](=[O:45])[CH2:43][CH2:44]3)[N:22]([c:25]3[cH:26][cH:27][c:28]([C:31]([C:32]([F:33])([F:34])[F:35])([CH3:36])[OH:37])[cH:29][cH:30]3)[CH2:23][CH2:24]2)[cH:13][cH:14][cH:15]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-38988bd9b80f4545b252bbf751f68c81
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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