Methanol → 2-[(2,3-dihydroxypropyl)amino]-6-(2-fluorophenoxy)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one
Reaction equation
[CH3:32][OH:33].[CH3:34][N:35]1[CH2:36][CH2:37][CH2:38][C:39]1=[O:40].[F:1][c:2]1[c:3]([O:4][c:5]2[cH:6][c:7]3[c:8]([n:9][c:10]([S:13]([CH3:14])(=[O:15])=[O:16])[n:11][cH:12]3)[n:17]([CH3:20])[c:18]2=[O:19])[cH:21][cH:22][cH:23][cH:24]1.[NH2:25][CH2:26][CH:27]([CH2:28][OH:29])[OH:30].[OH2:31]>>[F:1][c:2]1[c:3]([O:4][c:5]2[cH:6][c:7]3[c:8]([n:9][c:10]([NH:25][CH2:26][CH:27]([CH2:28][OH:29])[OH:30])[n:11][cH:12]3)[n:17]([CH3:20])[c:18]2=[O:19])[cH:21][cH:22][cH:23][cH:24]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-9b4569f02b9b40dcaa693c3ce77f3499
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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