Nitromethane → HCID 69417908, compound

HRID 1767566Notes

Reaction equation

HRID 1767566 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]2[N:14]3[C:9]([O:10][CH2:11][CH2:12][CH2:13]3)=[C:8]([CH:15]=O)[C:7]=2[N:17]=1.C([O-])(=O)C.[NH4+].[N+:23]([CH3:26])([O-:25])=[O:24]>>[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]2[N:14]3[C:9]([O:10][CH2:11][CH2:12][CH2:13]3)=[C:8]([CH:15]=[CH:26][N+:23]([O-:25])=[O:24])[C:7]=2[N:17]=1

Participants

4

Reactant 3

HCID 6375NitromethaneHCID 517165Ammonium AcetateHCID 12035116HCID 12035116, compound

Product 1

HCID 69417908HCID 69417908, compound

Procedure

300 mg (1.29 mmol) of the compound obtained in Step G dissolved in 15 ml of nitromethane are heated at 120° C. for 4 hours in the presence of 250 mg (3.23 mmol) of ammonium acetate. After returning to room temperature and evaporation to dryness, the reaction mixture is diluted in dichloromethane and washed with water. After drying over magnesium sulphate, evaporation of the organic phase yields the title compound in the form of a yellow solid.

Workup

  1. customAfter returning to room temperature
  2. customevaporation to dryness
  3. additionthe reaction mixture is diluted in dichloromethane
  4. washwashed with water
  5. dry with materialAfter drying over magnesium sulphate, evaporation of the organic phase

Sources & evidence

ORD record
ord-6b3faf6698c9448d806464ed934a87c0
Source dataset
uspto-grants-2007_06
Patent number
US07235550B2

Reaction notes

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