Myristyl bromide → HCID 178443153, compound

HRID 1774341Notes

Reaction equation

HRID 1774341 reaction equation
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([N:10]2[CH:14]=[CH:13][N:12]=[CH:11]2)=[CH:6][CH:5]=1)([O-:3])=[O:2].[Br:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH3:29]>C1COCC1>[Br-:15].[N+:1]([C:4]1[CH:5]=[CH:6][C:7]([N+:10]2[CH:14]=[CH:13][N:12]([CH2:29][CH2:28][CH2:27][CH2:26][CH2:25][CH2:24][CH2:23][CH2:22][CH2:21][CH2:20][CH2:19][CH2:18][CH2:17][CH3:16])[CH:11]=2)=[CH:8][CH:9]=1)([O-:3])=[O:2]

Participants

4

Reactant 2

HCID 8208Myristyl bromideHCID 1231551-(4-Nitrophenyl)-1H-imidazole

Product 1

HCID 178443153HCID 178443153, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

According to the general synthesis procedure, 5.3 mmol (1.00 g) 1-(4-nitrophenyl)imidazole and 6.3 mmol (1.76 g, 1.70 ml) 1-bromotetradecane are dissolved in 5 ml THF and heated for 45 h to 90° C. At the end of the reaction the reaction mixture is cooled down to room temperature and the precipitated product is washed with THF and diethylether.

Workup

  1. temperatureheated for 45 h to 90° C
  2. customAt the end of the reaction the reaction mixture
  3. washthe precipitated product is washed with THF and diethylether

Sources & evidence

ORD record
ord-fb10579894f846b9b14e4c296bb1a03a
Source dataset
uspto-grants-2016_02
Patent number
US09260397B2

Reaction notes

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