反应详情

In analogy to the procedure described for the preparation of intermediates A-12 [B], (S)-2-(2,2,2-trifluoro-ethoxymethyl)-pyrrolidine was reacted with 3-bromo-5-chloromethyl-pyridine (intermediate A-12 [A]) in presence of NaH to give the title compound as a yellow oil. MS: 353.1, 355.1 (M+H+).