反应详情

A solution of methyl 2-(methyl(4-(methylsulfonamido)benzyl)amino)acetate (0.977 g, 3.41 mmol) and HCl 6N (14.22 ml, 85 mmol) in dioxane (100 ml) was heated at 70° C. overnight. The solvent was removed and crude 2-(methyl(4-(methylsulfonamido)-benzyl)amino)acetic acid hydrochloride was obtained (1.054 g, 3.41 mmol, 100% yield, MS/ESI+ 273.1 [MH]+) and used in the next step without further purification.

1. customThe solvent was removed