Hydrochloric Acid → 1-(6-fluoro-3-pyridinyl)-N-[[4-(trifluoromethyl)phenyl]methyl]pyrrolidin-3-amine
Reaction equation
[BH4-:34].[CH3:27][CH2:28][N:29]([CH2:30][CH3:31])[CH2:32][CH3:33].[CH3:36][OH:37].[ClH:13].[F:14][c:15]1[cH:16][cH:17][c:18]([N:21]2[CH2:22][CH:23]([NH2:26])[CH2:24][CH2:25]2)[cH:19][n:20]1.[F:1][C:2]([c:3]1[cH:4][cH:5][c:6]([CH:7]=[O:8])[cH:9][cH:10]1)([F:11])[F:12].[Na+:35]>>[F:1][C:2]([c:3]1[cH:4][cH:5][c:6]([CH2:7][NH:26][CH:23]2[CH2:22][N:21]([c:18]3[cH:17][cH:16][c:15]([F:14])[n:20][cH:19]3)[CH2:25][CH2:24]2)[cH:9][cH:10]1)([F:11])[F:12]Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-7afda52fba8a44848fb001b17a7fbe62
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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