Hydrochloric Acid → HCID 19956421, compound

HRID 1779546Notes

Reaction equation

HRID 1779546 reaction equation
[CH2:1]([N:4](C(OC(C)(C)C)=O)[CH2:5][CH2:6][CH2:7][N:8](C(OC(C)(C)C)=O)[CH2:9]/[CH:10]=[CH:11]/[CH2:12][N:13](C(OC(C)(C)C)=O)[CH2:14][CH2:15][CH2:16][N:17]([CH2:25][CH2:26][CH3:27])C(OC(C)(C)C)=O)[CH:2]=[CH2:3].[ClH:49]>>[ClH:49].[ClH:49].[ClH:49].[ClH:49].[CH2:25]([NH:17][CH2:16][CH2:15][CH2:14][NH:13][CH2:12]/[CH:11]=[CH:10]/[CH2:9][NH:8][CH2:7][CH2:6][CH2:5][NH:4][CH2:1][CH2:2][CH3:3])[CH:26]=[CH2:27]

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 19956392HCID 19956392, compound

Product 1

HCID 19956421HCID 19956421, compound

Procedure

A mixture of 0.55 g (0.805 mmol) of (E)-1-allyl-14-propyl-1,5,10,14-tetra-BOC-1,5,10,14-tetraazatetradec-7-ene and 8.2 ml of 3N methanolic hydrochloric acid is reacted analogously to Example 8. The resulting title compound melts at >260° C. 1H-NMR (D2O): δ0.97(t,3H); 1.63-1.76(m,2H); 2.05-2.16(m,4H); 3.02(t,2H); 3.11-3.19(m,8H); 3.69(d,2H); 3.77(d,4H); 5.48-5.55(m,2H); 5.83-5.98(m,1H); 6.04-6.07(m,2H).

Workup

  1. customis reacted analogously to Example 8

Sources & evidence

ORD record
ord-0b98748c50d3440b9a120b7f6feeb193
Source dataset
uspto-grants-1997_05
Patent number
US05627215

Reaction notes

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