Acetone → 1-(4-fluorophenyl)-1,3-dihydro-1-[3-(tetrahydro-2H-pyran-2-yloxy)propyl]isobenzofuran
Reaction equation
[Br:26][CH2:27][CH2:28][CH2:29][O:30][CH:31]1[O:32][CH2:33][CH2:34][CH2:35][CH2:36]1.[C:5](=[O:6])=[O:7].[CH3:1][C:2](=[O:3])[CH3:4].[Cl-:37].[Cl:39][Fe:40]([Cl:41])[Cl:42].[F:10][c:11]1[cH:12][cH:13][c:14]([CH:17]2[O:18][CH2:19][c:20]3[cH:21][cH:22][cH:23][cH:24][c:25]32)[cH:15][cH:16]1.[NH3:8].[NH4+:38].[Na:9].[O:44]([CH2:45][CH3:46])[CH2:47][CH3:48].[OH2:43]>>[F:10][c:11]1[cH:12][cH:13][c:14]([C:17]2([CH2:27][CH2:28][CH2:29][O:30][CH:31]3[O:32][CH2:33][CH2:34][CH2:35][CH2:36]3)[O:18][CH2:19][c:20]3[cH:21][cH:22][cH:23][cH:24][c:25]32)[cH:15][cH:16]1Participants
12
Reactant 11
Product 1
Sources & evidence
- ORD record
- ord-1a170d6668b543ee9f89f6f0518ca18d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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