Hydrochloric Acid → HCID 19046249, compound

HRID 1781323Notes

Reaction equation

HRID 1781323 reaction equation
[N:1]1([CH2:13][CH2:14][NH:15][C:16](=[O:18])[CH3:17])[C:9]2[C:4](=[CH:5][CH:6]=[C:7]3[O:12][CH2:11][CH2:10][C:8]3=2)[CH2:3][CH2:2]1.[ClH:19]>C(OCC)(=O)C>[ClH:19].[N:1]1([CH2:13][CH2:14][NH:15][C:16](=[O:18])[CH3:17])[C:9]2[C:4](=[CH:5][CH:6]=[C:7]3[O:12][CH2:11][CH2:10][C:8]3=2)[CH2:3][CH2:2]1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 5311134N-[2-(2,3,7,8-Tetrahydrofuro[2,3-g]indol-1-yl)ethyl]acetamide

Product 1

HCID 19046249HCID 19046249, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

The title compound of Example 3 (334 mg) was dissolved in ethyl acetate (20 ml) and was treated with ethereal HCl (1.35 ml). This was stirred at room temperature for 2 h and then the solvent was evaporated to give the title compound as a pale green powder (383 mg), m.p. 152°-154° C.

Workup

  1. customthe solvent was evaporated

Sources & evidence

ORD record
ord-6f742d84ff9d4b8e8717082162d207dc
Source dataset
uspto-grants-1997_05
Patent number
US05633276

Reaction notes

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