Hydrochloric Acid → HCID 19045469, compound

HRID 1781430Notes

Reaction equation

HRID 1781430 reaction equation
C(N[N:5]1[CH2:10][CH2:9][C:8]2([CH:15]([CH3:16])[C:14](=[O:17])[C:13]3[CH:18]=[C:19]([S:22]([CH3:25])(=[O:24])=[O:23])[CH:20]=[CH:21][C:12]=3[O:11]2)[CH2:7][CH2:6]1)(=O)C.[ClH:26]>CO>[ClH:26].[CH3:16][CH:15]1[C:8]2([CH2:7][CH2:6][NH:5][CH2:10][CH2:9]2)[O:11][C:12]2[CH:21]=[CH:20][C:19]([S:22]([CH3:25])(=[O:24])=[O:23])=[CH:18][C:13]=2[C:14]1=[O:17]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 19045229HCID 19045229, compound

Product 1

HCID 19045469HCID 19045469, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

The product of Step B (0.5 g) in CH3OH (15 mL) and 6N HCl (15 mL) was heated at reflux for 10 hours. The reaction was concentrated to dryness. and the residue flushed with ethanol (4 times) and then toluene to yield 0.5 g of the title compound.

Workup

  1. temperatureat reflux for 10 hours
  2. concentrationThe reaction was concentrated to dryness
  3. customand the residue flushed with ethanol (4 times)

Sources & evidence

ORD record
ord-e0c45232d4d140a19e8b3300f46045d5
Source dataset
uspto-grants-1997_05
Patent number
US05633247

Reaction notes

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