Sodium ion → 4'-{[3-[2-(3-bromo-4-methoxyphenyl)-2-oxoethyl]-6-ethyl-2,4-dioxo-3,4-dihydrothieno[2,3-d]pyrimidin-1(2H)-yl]methyl}biphenyl-2-carbonitrile

HRID 178453Notes

Reaction equation

HRID 178453 reaction equation
[Br:29][CH2:30][C:31](=[O:32])[c:33]1[cH:34][c:35]([Br:41])[c:36]([O:39][CH3:40])[cH:37][cH:38]1.[CH2:1]([CH3:2])[c:3]1[cH:4][c:5]2[c:6]([n:7]([CH2:13][c:14]3[cH:15][cH:16][c:17](-[c:20]4[c:21]([C:26]#[N:27])[cH:22][cH:23][cH:24][cH:25]4)[cH:18][cH:19]3)[c:8](=[O:12])[nH:9][c:10]2=[O:11])[s:28]1.[CH3:42][N:43]([CH3:44])[CH:45]=[O:46].[CH3:49][CH2:50][O:51][C:52](=[O:53])[CH3:54].[H-:47].[Na+:48]>>[CH2:1]([CH3:2])[c:3]1[cH:4][c:5]2[c:6]([n:7]([CH2:13][c:14]3[cH:15][cH:16][c:17](-[c:20]4[c:21]([C:26]#[N:27])[cH:22][cH:23][cH:24][cH:25]4)[cH:18][cH:19]3)[c:8](=[O:12])[n:9]([CH2:30][C:31](=[O:32])[c:33]3[cH:34][c:35]([Br:41])[c:36]([O:39][CH3:40])[cH:37][cH:38]3)[c:10]2=[O:11])[s:28]1

Participants

7

Reactant 6

HCID 923Sodium ionHCID 6228DimethylformamideHCID 8857Ethyl AcetateHCID 166653HydrideHCID 27568492-Bromo-1-(3-bromo-4-methoxyphenyl)ethanoneHCID 593517704'-[(6-ethyl-2,4-dioxo-3,4-dihydrothieno[2,3-d]pyrimidin-1(2H)-yl)methyl]biphenyl-2-carbonitrile

Product 1

HCID 593516184'-{[3-[2-(3-bromo-4-methoxyphenyl)-2-oxoethyl]-6-ethyl-2,4-dioxo-3,4-dihydrothieno[2,3-d]pyrimidin-1(2H)-yl]methyl}biphenyl-2-carbonitrile

Sources & evidence

ORD record
ord-f5660733c6c6416e8741fff96e8f90af
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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