Hydrazine hydrate (1:1) → HCID 45119106, compound

HRID 1786246Notes

Reaction equation

HRID 1786246 reaction equation
C[O:2][C:3](=O)[CH:4]([C:6]([F:9])([F:8])[F:7])[OH:5].O.[NH2:12][NH2:13]>C(O)CCC>[F:7][C:6]([F:9])([F:8])[CH:4]([OH:5])[C:3]([NH:12][NH2:13])=[O:2]

Participants

4

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 2760118methyl 3,3,3-trifluoro-dl-lactate

Product 1

HCID 45119106HCID 45119106, compound

Reagents, catalysts & solvents 1

HCID 2631-ButanolSolvent

Procedure

As described for example 112a, methyl-3,3,3-trifluoro-DL-lactate in butanol was reacted with hydrazine hydrate (1.2 equivalents) at rt for 16 h. The mixture was concentrated and the title compound was obtained as a light yellow oil (yield: 81%). MS: m/e=158.0 [M]+.

Workup

  1. concentrationThe mixture was concentrated

Sources & evidence

ORD record
ord-3ed0c45c9a6c4e9cb8a5baa9d1aa71a3
Source dataset
uspto-grants-2009_03
Patent number
US07507729B2

Reaction notes

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