Hydrogen Peroxide → Monoperoxyphthalic acid

HRID 1786778Notes

Reaction equation

HRID 1786778 reaction equation
[C:1]1(=[O:11])[O:6][C:4](=[O:5])[C:3]2=[CH:7][CH:8]=[CH:9][CH:10]=[C:2]12.[OH:12][OH:13]>C(OCC)C>[CH:9]1[CH:10]=[C:2]([C:1]([OH:6])=[O:11])[C:3]([C:4]([O:12][OH:13])=[O:5])=[CH:7][CH:8]=1

Participants

4

Reactant 2

HCID 784Hydrogen PeroxideHCID 6811Phthalic Anhydride

Product 1

HCID 75329Monoperoxyphthalic acid

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Conditions

Temperature
25 °C

Procedure

To the mixture containing phthalic anhydride (2.22 g, 0.015 mole) and diethyl ether (25 mL), hydrogen peroxide solution (3.4 g; 0.03 moles; as 30% aqueous solution) was added and the reaction mixture was stirred at 25° C. to dissolve the anhydride. The reaction mixture was transferred to a separating funnel, ether layer was separated and aqueous layer was extracted with ether (3×10 mL). Combined ether extracts are dried over sodium sulfate and this solution of monoperphthalic acid was used.

Workup

  1. additionwas added
  2. customThe reaction mixture was transferred to a separating funnel
  3. customether layer was separated
  4. extractionaqueous layer was extracted with ether (3×10 mL)
  5. dry with materialCombined ether extracts are dried over sodium sulfate

Sources & evidence

ORD record
ord-307b913c1d1f4958823e855ed6e1c938
Source dataset
uspto-grants-2009_03
Patent number
US07507835B2

Reaction notes

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